HLA typing in a Kenyan cohort identifies novel class I alleles that restrict cytotoxic T-cell responses to local HIV-1 clades.

OBJECTIVES: To investigate HLA class I allele frequencies in a Kenyan commercial sex worker (CSW) cohort, and to examine HIV-1 specific cytotoxic T lymphocyte (CTL) responses directed against epitopes derived from locally prevalent clade A virus. METHODS: PCR-single strand polymorphism HLA class I...

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Bibliographic Details
Main Authors: Bird, T, Kaul, R, Rostron, T, Kimani, J, Embree, J, Dunn, P, Bwayo, J, Plummer, F, Rowland-Jones, S, Dong, T
Format: Journal article
Language:English
Published: 2002