Structure of bacterial 3beta/17beta-hydroxysteroid dehydrogenase at 1.2 A resolution: a model for multiple steroid recognition.

The enzyme 3beta/17beta-hydroxysteroid dehydrogenase (3beta/17beta-HSD) is a steroid-inducible component of the Gram-negative bacterium Comamonas testosteroni. It catalyzes the reversible reduction/dehydrogenation of the oxo/beta-hydroxy groups at positions 3 and 17 of steroid compounds, including h...

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Bibliographic Details
Main Authors: Benach, J, Filling, C, Oppermann, U, Roversi, P, Bricogne, G, Berndt, K, Jörnvall, H, Ladenstein, R
Format: Journal article
Language:English
Published: 2002