An estimate of the turnover rate of bone-derived plasma alkaline phosphatase in Paget's disease.

A through-knee amputation for suspected osteogenic sarcoma was performed on a patient with Paget's disease of the tibia. Plasma alkaline phosphatase (AP) activity fell to normal values, apparently as a single exponential function of time, with a half-life of 1.7 days. The daily turnover of bone...

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Bibliographic Details
Main Authors: Walton, R, Preston, C, Russell, R, Kanis, J
Format: Journal article
Language:English
Published: 1975