Solution conformation of a parallel DNA triple helix with 5' and 3' triplex-duplex junctions.
BACKGROUND: Polypurine x polypyrimidine sequences of DNA can form parallel triple helices via Hoogsteen hydrogen bonds with a third DNA strand that is complementary to the purine strand. The triplex prevents transcription and could therefore potentially be used to regulate specific genes. The determ...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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