Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering.
CD4 and CD8 are thought to function as coreceptors by binding to the cognate major histocompatibility complex (MHC) molecules recognized by the T cell antigen receptor (TCR) and initiating the signal transduction cascade. We report that during T cell-antigen-presenting cell interaction, triggered TC...
Main Authors: | Viola, A, Salio, M, Tuosto, L, Linkert, S, Acuto, O, Lanzavecchia, A |
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Format: | Journal article |
Language: | English |
Published: |
1997
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