The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release.

The regulation of Ca(2+) release by luminal Ca(2+) has been well studied for the ryanodine and IP(3) receptors but has been less clear for the NAADP-regulated channel. In view of conflicting reports, we have re-examined the issue by manipulating luminal Ca(2+) with the membrane-permeant, low affinit...

Повний опис

Бібліографічні деталі
Автори: Morgan, A, Parrington, J, Galione, A
Формат: Journal article
Мова:English
Опубліковано: 2012