The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release.
The regulation of Ca(2+) release by luminal Ca(2+) has been well studied for the ryanodine and IP(3) receptors but has been less clear for the NAADP-regulated channel. In view of conflicting reports, we have re-examined the issue by manipulating luminal Ca(2+) with the membrane-permeant, low affinit...
| Main Authors: | , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2012
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