Gene transfer vector development to treat lung disease: The use of a dual-function Lentiviral vector containing ENaC RNAi and the CFTR gene to treat Cystic Fibrosis lung disaease

<p>Cystic Fibrosis (CF) is a degenerative disorder that is often associated with chronic lung disease. CF is caused by mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) chloride channel, which lead to defective chloride and sodium ion movement across...

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Bibliographic Details
Main Author: Harding-Smith, R
Other Authors: Gill, D
Format: Thesis
Language:English
Published: 2014
Subjects: