A dynamic view of the immunological synapse.

T cell activation requires interactions of T cell antigen receptors (TCR) and peptides presented by major histocompatibility complex molecules (MHCp) in an adhesive junction between the T cell and antigen-presenting cell. Stable junctions with bull's eye supramolecular activation clusters (SMAC...

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Bibliographic Details
Main Author: Dustin, M
Format: Journal article
Language:English
Published: 2005