18F-trifluoromethylation of unmodified peptides with 5-18F-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate

The 18F-labeling of 5-(trifluoromethyl)-dibenzothiophenium trifluoromethanesulfonate, commonly referred to as the Umemoto reagent, has been accomplished applying a halogen exchange 18F-fluorination with 18F-fluoride, followed by oxidative cyclization with Oxone and trifluoromethanesulfonic anhydride...

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Bibliographic Details
Main Authors: Verhoog, S, Kee, C, Wang, Y, Khotavivattana, T, Wilson, T, Kersemans, V, Smart, S, Tredwell, M, Davis, B, Gouverneur, V
Format: Journal article
Language:English
Published: American Chemical Society 2018