Cytokine production by human colonic intraepithelial lymphocytes in controls and ulcerative colitis.

Using an ELISA technique, concentrations of gamma-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of gamma-interferon and interleukin-2 when...

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מידע ביבליוגרפי
Main Authors: Hoang, P, Dalton, H, de Silv, H, Jewell, D
פורמט: Journal article
שפה:English
יצא לאור: 1994
תיאור
סיכום:Using an ELISA technique, concentrations of gamma-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of gamma-interferon and interleukin-2 when stimulated with PHA, but significantly more than when unstimulated (p < 0.05). There was no difference in production of these cytokines by IEL from control or inflammatory bowel disease.