Phospholipase C-dependent Ca2+ release by worm and mammal sperm factors.

Egg activation in all animals evidently requires the synthesis of inositol 1,4,5-trisphosphate (InsP(3)) from phosphatidylinositol 4,5-bisphosphate (PIP(2)) by phospholipase C (PLC). Depending on the organism, InsP(3) elicits either calcium oscillations or a single wave, which in turn initiates deve...

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Bibliographic Details
Main Authors: Howell, K, Skipwith, A, Galione, A, Eckberg, W
Format: Journal article
Language:English
Published: 2003