Expression of the plasma cell transcriptional regulator Blimp-1 by dark zone germinal center B cells during periods of proliferation

Long-lived plasma cells (PCs) develop in germinal centers (GCs) by the differentiation of affinity matured B cells. Antibody affinity maturation involves iterative rounds of somatic hypermutation in dark zones (DZs) and selection in light zones (LZs), however the details of where, when and how PC co...

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Bibliografische gegevens
Hoofdauteurs: Radtke, D, Bannard, O
Formaat: Journal article
Gepubliceerd in: Frontiers Media 2019