Role of HIV-specific CD8(+) T cells in pediatric HIV cure strategies after widespread early viral escape

Recent studies have suggested greater HIV cure potential among infected children than adults. A major obstacle to HIV eradication in adults is that the viral reservoir is largely comprised of HIV-specific cytotoxic T lymphocyte (CTL) escape variants. We here evaluate the potential for CTL in HIV-inf...

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Bibliographic Details
Main Authors:	Leitman, E, Thobakgale, C, Adland, E, Ansari, M, Raghwani, J, Prendergast, A, Tudor-Williams, G, Kiepiela, P, Hemelaar, J, Brener, J, Tsai, M, Mori, M, Riddell, L, Luzzi, G, Jooste, P, Ndung'u, T, Walker, B, Pybus, O, Kellam, P, Naranbhai, V, Matthews, P, Gall, A, Goulder, P
Format:	Journal article
Language:	English
Published:	Rockefeller University Press 2017

Role of HIV-specific CD8(+) T cells in pediatric HIV cure strategies after widespread early viral escape

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