The synthesis of (+/-)-heliotridane and (6S,7S)-dihydroxyheliotridane via sequential hydrogen atom abstraction and cyclisation

The synthesis of (+/-)-heliotridane and (6S,7S)-dihydroxyheliotridane via sequential hydrogen atom abstraction and cyclisation

Treatment of N-(3-bromo-3-butenyl)pyrrolidine derivatives with tributyltin hydride and AIBN leads to hydrogen atom transfer of the intermediate vinyl radicals to give α-amino radicals which then cyclise stereoselectively yielding pyrrolizidines 1 and 13.

书目详细资料
Main Authors:	Robertson, J, Peplow, M, Pillai, J
格式:	Journal article
语言:	English
出版:	1996

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