Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.

Mammalian SWI/SNF [also called Brg/Brahma-associated factors (BAFs)] are evolutionarily conserved chromatin-remodeling complexes regulating gene transcription programs during development and stem cell differentiation. BAF complexes contain an ATP (adenosine 5'-triphosphate)-driven remodeling en...

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Bibliographic Details
Main Authors:	Fedorov, O, Castex, J, Tallant, C, Owen, D, Martin, S, Aldeghi, M, Monteiro, O, Filippakopoulos, P, Picaud, S, Trzupek, J, Gerstenberger, B, Bountra, C, Willmann, D, Wells, C, Philpott, M, Rogers, C, Biggin, P, Brennan, P, Bunnage, M, Schüle, R, Günther, T, Knapp, S, Müller, S
Format:	Journal article
Language:	English
Published:	American Association for the Advancement of Science 2015

Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.

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