Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.
Mammalian SWI/SNF [also called Brg/Brahma-associated factors (BAFs)] are evolutionarily conserved chromatin-remodeling complexes regulating gene transcription programs during development and stem cell differentiation. BAF complexes contain an ATP (adenosine 5'-triphosphate)-driven remodeling en...
Үндсэн зохиолчид: | , , , , , , , , , , , , , , , , , , , , , , |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
American Association for the Advancement of Science
2015
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