Asymmetric total synthesis of (−)-(3R)-inthomycin C

A short (10 step) and efficient (15% overall yield) synthesis of the natural product (−)-(3R)-inthomycin C is reported. The key steps comprise three C–C bond-forming reactions: (i) a vinylogous Mukaiyama aldol, (ii) an olefin cross-metathesis reaction, and (iii) an asymmetric Mukaiyama–Kiyooka aldol...

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Xehetasun bibliografikoak
Egile Nagusiak: Balcells, S, Haughey, M, Walker, J, Josa-Cullere, L, Towers, C, Donohoe, T
Formatua: Journal article
Argitaratua: American Chemical Society 2018