Asymmetric total synthesis of (−)-(3R)-inthomycin C
A short (10 step) and efficient (15% overall yield) synthesis of the natural product (−)-(3R)-inthomycin C is reported. The key steps comprise three C–C bond-forming reactions: (i) a vinylogous Mukaiyama aldol, (ii) an olefin cross-metathesis reaction, and (iii) an asymmetric Mukaiyama–Kiyooka aldol...
Egile Nagusiak: | , , , , , |
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Formatua: | Journal article |
Argitaratua: |
American Chemical Society
2018
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