Beyond PARP—POLθ as an anticancer target

Since the discovery that DNA is unstable and prone to decay, targeting DNA repair deficiencies has become a proven and effective strategy in the fight against cancer. Over the past decades, it has become increasingly apparent that selective loss of DNA repair pathways is an early and frequent event...

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Bibliographic Details
Main Authors: Higgins, G, Boulton, S
Format: Journal article
Published: American Association for the Advancement of Science 2018