Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao(-/-) ) mice

A common strategy when searching for cognitive-enhancing drugs has been to target the N-methyl-d-aspartate receptor (NMDAR), given its putative role in synaptic plasticity and learning. Evidence in favour of this approach has come primarily from studies with rodents using behavioural assays like the...

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Bibliographic Details
Main Authors: Pritchett, D, Taylor, A, Barkus, C, Engle, S, Brandon, N, Sharp, T, Foster, R, Harrison, P, Peirson, SN, Bannerman, D
Format: Journal article
Language:English
Published: Wiley 2016