Functional characterization of 4 polymorphisms in promoter region of hepatic lipase gene.

Hepatic lipase (HL) is a lipolytic enzyme involved in the metabolism of plasma lipoproteins, especially high density lipoproteins. Association studies have provided strong evidence for relations of common mutations in the promoter region of the HL gene to postheparin plasma HL activity and the plasm...

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Main Authors: van't Hooft, F, Lundahl, B, Ragogna, F, Karpe, F, Olivecrona, G, Hamsten, A
Format: Journal article
Jezik:English
Izdano: 2000