Widespread impact of HLA restriction on immune control and escape pathways of HIV-1.
The promiscuous presentation of epitopes by similar HLA class I alleles holds promise for a universal T-cell-based HIV-1 vaccine. However, in some instances, cytotoxic T lymphocytes (CTL) restricted by HLA alleles with similar or identical binding motifs are known to target epitopes at different fre...
| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
2012
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