Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group.

BACKGROUND: Neutralization of tumor necrosis factor a (TNF-alpha) for three to six months reduces the symptoms and signs of rheumatoid arthritis. However, the capacity of this approach to effect a more sustained benefit and its effect on joint damage are not known. METHODS: We treated 428 patients...

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Bibliographic Details
Main Authors: Lipsky, P, van der Heijde, D, St Clair, E, Furst, D, Breedveld, F, Kalden, JR, Smolen, J, Weisman, M, Emery, P, Feldmann, M, Harriman, G, Maini, R
Format: Journal article
Language:English
Published: 2000