IL-2/B7.1 (CD80) fusagene transduction of AML blasts by a self-inactivating lentiviral vector stimulates T cell responses in vitro: a strategy to generate whole cell vaccines for AML.

Combined expression of costimulatory factors and proinflammatory cytokines stimulate effective immune-mediated tumor rejection in a variety of murine tumor models. Specifically, syngeneic tumor cells genetically modified to express B7.1 (CD80) have been shown to induce rejection of previously establ...

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Detalhes bibliográficos
Principais autores: Chan, L, Hardwick, N, Darling, D, Galea-Lauri, J, Gäken, J, Devereux, S, Kemeny, M, Mufti, G, Farzaneh, F
Formato: Journal article
Idioma:English
Publicado em: 2005