Reversible ligation of programmed DNA-gold nanoparticle assemblies

We demonstrate a new method to reversibly cross-link DNA-nanoparticle dimers, trimers, and tetramers using light as an external stimulus. A DNA interstrand photo-cross-linking reaction is possible via ligation of a cyano-vinyl carbazole nucleoside with an opposite thymine when irradiated at 365 nm....

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Autori principali: Harimech, P, Gerrard, S, El-Sagheer, A, Brown, T, Kanaras, A
Natura: Journal article
Lingua:English
Pubblicazione: American Chemical Society 2015