Modelling DNA origami self-assembly at the domain level

We present a modelling framework, and basic model parameterization, for the study of DNA origami folding at the level of DNA domains. Our approach is explicitly kinetic and does not assume a specific folding pathway. The binding of each staple is associated with a free-energy change that depends on...

Full description

Bibliographic Details
Main Authors: Dannenberg, F, Dunn, KE, Bath, J, Kwiatkowska, M, Turberfield, AJ, Ouldridge, TE
Format: Journal article
Language:English
Published: American Institute of Physics 2015