Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial.
BACKGROUND: Primaquine is the only available drug that clears mature Plasmodium falciparum gametocytes in infected human hosts, thereby preventing transmission of malaria to mosquitoes. However, concerns about dose-dependent haemolysis in people with glucose-6-phosphate dehydrogenase (G6PD) deficien...
Autori principali: | Eziefula, A, Bousema, T, Yeung, S, Kamya, M, Owaraganise, A, Gabagaya, G, Bradley, J, Grignard, L, Lanke, K, Wanzira, H, Mpimbaza, A, Nsobya, S, White, N, Webb, E, Staedke, S, Drakeley, C |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
Elsevier
2014
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