Protein kinase A type I and type II define distinct intracellular signaling compartments.

Protein kinase A (PKA) is a key regulatory enzyme that, on activation by cAMP, modulates a wide variety of cellular functions. PKA isoforms type I and type II possess different structural features and biochemical characteristics, resulting in nonredundant function. However, how different PKA isoform...

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Bibliographic Details
Main Authors: Di Benedetto, G, Zoccarato, A, Lissandron, V, Terrin, A, Li, X, Houslay, MD, Baillie, G, Zaccolo, M
Format: Journal article
Language:English
Published: 2008