Protein kinase A type I and type II define distinct intracellular signaling compartments.

Protein kinase A type I and type II define distinct intracellular signaling compartments.

Protein kinase A (PKA) is a key regulatory enzyme that, on activation by cAMP, modulates a wide variety of cellular functions. PKA isoforms type I and type II possess different structural features and biochemical characteristics, resulting in nonredundant function. However, how different PKA isoform...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Di Benedetto, G, Zoccarato, A, Lissandron, V, Terrin, A, Li, X, Houslay, MD, Baillie, G, Zaccolo, M
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2008

Những quyển sách tương tự

A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells.
Bằng: Wilson, L, et al.
Được phát hành: (2011)

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases.
Bằng: Mongillo, M, et al.
Được phát hành: (2004)

Restricted diffusion of a freely diffusible second messenger: Mechanisms underlying compartmentalized cAMP signalling
Bằng: Zaccolo, M, et al.
Được phát hành: (2006)

Restricted diffusion of a freely diffusible second messenger: mechanisms underlying compartmentalized cAMP signalling.
Bằng: Zaccolo, M, et al.
Được phát hành: (2006)

Imaging the cAMP-dependent signal transduction pathway
Bằng: Zaccolo, M, et al.
Được phát hành: (2005)

Imaging the cAMP-dependent signal transduction pathway.
Bằng: Zaccolo, M, et al.
Được phát hành: (2005)

Redox-dependent signalling via protein Kinase A type I within distinct subcellular compartments
Bằng: Lomas, O
Được phát hành: (2016)

PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases.
Bằng: Terrin, A, et al.
Được phát hành: (2006)

Measuring dynamic changes in cAMP using fluorescence resonance energy transfer.
Bằng: Evellin, S, et al.
Được phát hành: (2004)

Study of cyclic adenosine monophosphate microdomains in cells.
Bằng: Mongillo, M, et al.
Được phát hành: (2005)

cGMP signals modulate cAMP levels in a compartment-specific manner to regulate catecholamine-dependent signaling in cardiac myocytes.
Bằng: Stangherlin, A, et al.
Được phát hành: (2011)

Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments
Bằng: William S. Garver, et al.
Được phát hành: (2000-05-01)

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway.
Bằng: Mongillo, M, et al.
Được phát hành: (2006)

Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
Bằng: Bullock, A, et al.
Được phát hành: (2009)

Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation
Bằng: Bullock, A, et al.
Được phát hành: (2009)

The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations.
Bằng: Oliveira, R, et al.
Được phát hành: (2010)

RNA splicing programs define tissue compartments and cell types at single-cell resolution
Bằng: Julia Eve Olivieri, et al.
Được phát hành: (2021-09-01)

Improvement of a FRET-based indicator for cAMP by linker design and stabilization of donor-acceptor interaction.
Bằng: Lissandron, V, et al.
Được phát hành: (2005)

PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome.
Bằng: Terrin, A, et al.
Được phát hành: (2012)

Compartmentalized cAMP/PKA signalling regulates cardiac excitation-contraction coupling.
Bằng: Lissandron, V, et al.
Được phát hành: (2006)

The Distribution and Role of the CFTR Protein in the Intracellular Compartments
Bằng: Agnieszka Lukasiak, et al.
Được phát hành: (2021-10-01)

Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors
Bằng: Gesellchen, F, et al.
Được phát hành: (2011)

Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors.
Bằng: Gesellchen, F, et al.
Được phát hành: (2011)

Small-molecule FRET probes for protein kinase activity monitoring in living cells.
Bằng: Vaasa, A, et al.
Được phát hành: (2010)

GPCRs in Intracellular Compartments: New Targets for Drug Discovery
Bằng: Irene Fasciani, et al.
Được phát hành: (2022-09-01)

Shapes of discoid intracellular compartments with small relative volumes.
Bằng: Jure Derganc, et al.
Được phát hành: (2011-01-01)

cAMP signaling in subcellular compartments.
Bằng: Lefkimmiatis, K, et al.
Được phát hành: (2014)

PKA microdomain organisation and cAMP handling in healthy and dystrophic muscle in vivo.
Bằng: Röder, I, et al.
Được phát hành: (2009)

Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways
Bằng: Harish N Vasudevan, et al.
Được phát hành: (2015-05-01)

Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments.
Bằng: Corina M Stewart, et al.
Được phát hành: (2021-01-01)

Analysis of compartmentalized cAMP: A method to compare signals from differently targeted FRET reporters
Bằng: Stangherlin, A, et al.
Được phát hành: (2014)

Analysis of compartmentalized cAMP: a method to compare signals from differently targeted FRET reporters.
Bằng: Stangherlin, A, et al.
Được phát hành: (2014)

NUTRITION IN TYPE II DIABETES MELLITUS THE ELEPHANT IN THE ROOM
Bằng: Peter Baillie
Được phát hành: (2024-10-01)

NUTRITION IN TYPE II DIABETES MELLITUS THE ELEPHANT IN THE ROOM
Bằng: Peter Baillie
Được phát hành: (2024-10-01)

PU.1 Expression Defines Distinct Functional Activities in the Phenotypic HSC Compartment of a Murine Inflammatory Stress Model
Bằng: James S. Chavez, et al.
Được phát hành: (2022-02-01)

Creatine Kinase Activity in Patients with Diabetes Mellitus Type I and Type II
Bằng: Adlija Jevrić-Čaušević, et al.
Được phát hành: (2006-08-01)

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes.
Bằng: Sin, Y, et al.
Được phát hành: (2011)

Cellular census of human fibrosis defines functionally distinct stromal cell types and states
Bằng: Layton, TB, et al.
Được phát hành: (2020)

Cellular census of human fibrosis defines functionally distinct stromal cell types and states
Bằng: Thomas B. Layton, et al.
Được phát hành: (2020-06-01)

Self-assembled hydrogel fibers for sensing the multi-compartment intracellular milieu
Bằng: Vemula, Praveen Kumar, et al.
Được phát hành: (2014)