Dynamic regulation of CD28 conformation and signaling by charged lipids and ions

Dynamic regulation of CD28 conformation and signaling by charged lipids and ions

CD28 provides an essential co-stimulatory signal for T cell activation and its function is critical in antitumor immunity. However, the molecular mechanism of CD28 transmembrane signaling remains elusive. Here, we find that CD28 conformation and signaling are regulated by two counteractive charge...

書誌詳細
主要な著者:	Yang, W, Pan, W, Chen, S, Trendel, N, Jiang, S, Xiao, F, Xue, M, Wu, W, Peng, Z, Li, X, Ji, H, Liu, X, Jiang, H, Wang, H, Shen, H, Dushek, O, Li, H, Xu, C
フォーマット:	Journal article
出版事項:	Springer Nature 2017

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