Genetic variants of glucose-6-phosphate dehydrogenase and their associated enzyme activity: a systematic review and meta-analysis

Low glucose-6-phosphate dehydrogenase enzyme (G6PD) activity is a key determinant of drug-induced haemolysis. More than 230 clinically relevant genetic variants have been described. We investigated the variation in G6PD activity within and between different genetic variants. In this systematic revie...

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Κύριοι συγγραφείς: Pfeffer, DA, Satyagraha, AW, Sadhewa, A, Alam, MS, Bancone, G, Boum, Y, Brito, M, Cui, L, Deng, Z, Domingo, GJ, He, Y, Khan, WA, Kibria, MG, Lacerda, M, Menard, D, Monteiro, W, Pal, S, Parikh, S, Roca-Feltrer, A, Roh, M, Sirdah, MM, Wang, D, Huang, Q, Howes, RE, Price, RN, Ley, B
Μορφή: Journal article
Γλώσσα:English
Έκδοση: MDPI 2022