A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex

Nipah virus (NiV) is a highly pathogenic paramyxovirus that causes frequent outbreaks of severe neurologic and respiratory disease in humans with high case fatality rates. The 2 glycoproteins displayed on the surface of the virus, NiV-G and NiV-F, mediate host-cell attachment and membrane fusion, re...

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Bibliographic Details
Main Authors: Avanzato, V, Oguntuyo, K, Escalera-Zamudio, M, Gutierrez, B, Golden, M, Kosakovsky Pond, S, Pryce, R, Walter, T, Seow, J, Doores, K, Pybus, O, Munster, V, Lee, B, Bowden, T
Format: Journal article
Language:English
Published: National Academy of Sciences 2019