Comparison of T cell activities mediated by human TCRs and CARs that use the same recognition domains
Adoptive T cell therapies have achieved significant clinical responses, especially in hematopoietic cancers. Two types of receptor systems have been used to redirect the activity of T cells, normal heterodimeric T-cell receptors (TCRs) or synthetic chimeric antigen receptors (CARs). TCRs recognize p...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
American Association of Immunologists
2017
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