Strain selection for generation of O-antigen-based glycoconjugate vaccines against invasive nontyphoidal salmonella disease

Nontyphoidal Salmonellae, principally S. Typhimurium and S. Enteritidis, are a major cause of invasive bloodstream infections in sub-Saharan Africa with no vaccine currently available. Conjugation of lipopolysaccharide O-antigen to a carrier protein constitutes a promising vaccination strategy. Here...

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Bibliographic Details
Main Authors: Lanzilao, L, Stefanetti, G, Saul, A, MacLennan, C, Micoli, F, Rondini, S
Format: Journal article
Language:English
Published: Public Library of Science 2015