FTO genotype is associated with phenotypic variability of body mass index.

FTO genotype is associated with phenotypic variability of body mass index.

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There is evidence across several species for genetic control of phenotypic variation of complex traits, such that the variance among phenotypes is genotype dependent. Understanding genetic control of variability is important in evolutionary biology, agricultural selection programmes and human medici...

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Bibliografische gegevens
Hoofdauteurs:	Yang, J, Loos, R, Powell, J, Medland, SE, Speliotes, E, Chasman, D, Rose, L, Thorleifsson, G, Steinthorsdottir, V, Mägi, R, Waite, L, Smith, A, Yerges-Armstrong, L, Monda, K, Hadley, D, Mahajan, A, Li, G, Kapur, K, Vitart, V, Huffman, J, Wang, SR, Palmer, C, Esko, T, Fischer, K, Zhao, J
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2012

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FTO genotype is associated with phenotypic variability of body mass index
door: Yang, J, et al.
Gepubliceerd in: (2012)

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
door: Heid, I, et al.
Gepubliceerd in: (2010)

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
door: Heid, I, et al.
Gepubliceerd in: (2011)

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
door: Heid, I, et al.
Gepubliceerd in: (2010)

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (Nature Genetics (2010) 42 (949-960))
door: Heid, I, et al.
Gepubliceerd in: (2011)

To Stratify Or Not To Stratify: What Can Be Learned From Power Considerations And A Practical Genome-Wide Search On Sex-Difference In The GIANT Consortium
door: Heid, I, et al.
Gepubliceerd in: (2012)

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
door: Speliotes, E, et al.
Gepubliceerd in: (2010)

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
door: Speliotes, E, et al.
Gepubliceerd in: (2010)

Association of FTO and PPARG polymorphisms with obesity in Portuguese women
door: Ferreira Carlos F, et al.
Gepubliceerd in: (2013-07-01)

FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians.
door: Yajnik, C, et al.
Gepubliceerd in: (2009)

Changes in gene expression associated with FTO overexpression in mice
door: Merkestein, M, et al.
Gepubliceerd in: (2014)

Overexpression of Fto leads to increased food intake and results in obesity.
door: Church, C, et al.
Gepubliceerd in: (2010)

FTO in health and disease
door: Daniel Benak, et al.
Gepubliceerd in: (2024-12-01)

Hypothalamic FTO is associated with the regulation of energy intake not feeding reward
door: Radomska Katarzyna J, et al.
Gepubliceerd in: (2009-10-01)

Association of rs9939609 polymorphism in the FTO gene with features of androgen status in men
door: S. V. Yankovskaya, et al.
Gepubliceerd in: (2022-04-01)

Inhibition and mechanistic studies of FTO
door: Shishodia, S
Gepubliceerd in: (2017)

Comprehensive mutations analyses of FTO (fat mass and obesity-associated gene) and their effects on FTO’s substrate binding implicated in obesity
door: Rakesh Kumar, et al.
Gepubliceerd in: (2022-07-01)

Functional analysis of the fat mass and obesity associated (Fto) gene and protein
door: Stasiak, L
Gepubliceerd in: (2015)

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
door: Claussnitzer, Melina, et al.
Gepubliceerd in: (2016)

FTO Gene Polymorphisms Contribute to the Predisposition and Radiotherapy Efficiency of Nasopharyngeal Carcinoma
door: Xiao F, et al.
Gepubliceerd in: (2021-09-01)

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.
door: Yi-Chun Loraine Tung, et al.
Gepubliceerd in: (2010-01-01)

Regulation of Fto/Ftm gene expression in mice and humans.
door: Stratigopoulos, G, et al.
Gepubliceerd in: (2008)

FTO and Anthropometrics: The Role of Modifiable Factors
door: Cassandra Evans, et al.
Gepubliceerd in: (2022-10-01)

THE ROLE OF THE DEMETHYLASE FTO IN NEURONAL FUNCTION.
door: Lucía Pérez-Benítez, et al.
Gepubliceerd in: (2023-10-01)

FTO associations with obesity and telomere length
door: Yuling Zhou, et al.
Gepubliceerd in: (2017-09-01)

The Association of FTO SNP rs9939609 with Weight Gain at University
door: Susanne F. Meisel, et al.
Gepubliceerd in: (2015-07-01)

The Role of FTO Genotype in the Association Between FTO Gene Expression and Anthropometric Measures in Obese and Overweight Adolescent Boys
door: Saeid Doaei, et al.
Gepubliceerd in: (2019-02-01)

SiFTO: An empirical method for fitting SN Ia light curves
door: Conley, A, et al.
Gepubliceerd in: (2008)

SiFTO: An empirical method for fitting SN Ia light curves
door: Conley, A, et al.
Gepubliceerd in: (2008)

A common variant in the FTO locus is associated with waist-hip ratio in Indian adolescents
door: Vasan, S, et al.
Gepubliceerd in: (2013)

A common variant in the FTO locus is associated with waist-hip ratio in Indian adolescents.
door: Vasan, S, et al.
Gepubliceerd in: (2013)

Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo
door: Laber, S, et al.
Gepubliceerd in: (2021)

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.
door: Tönjes, A, et al.
Gepubliceerd in: (2010)

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany
door: Tönjes, A, et al.
Gepubliceerd in: (2010)

FTO Gene Polymorphisms Contribute to the Predisposition and Radiotherapy Efficiency of Nasopharyngeal Carcinoma [Retraction]
door: Xiao F, et al.
Gepubliceerd in: (2021-12-01)

Effects of FTO and PPARγ variants on intrauterine growth restriction in a Brazilian birth cohort
door: M.R. Barbieri, et al.
Gepubliceerd in: (2021-03-01)

Differences in brain structure and function in children with the FTO obesity‐risk allele
door: Claudia Lugo‐Candelas, et al.
Gepubliceerd in: (2020-08-01)

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.
door: Church, C, et al.
Gepubliceerd in: (2009)

FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting.
door: McTaggart, J, et al.
Gepubliceerd in: (2011)

Dietary energy density affects fat mass in early adolescence and is not modified by FTO variants
door: Johnson, L, et al.
Gepubliceerd in: (2009)