Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease.

BACKGROUND: Alternative gene transcript splicing permits a single gene to produce multiple proteins with varied functions. Bioinformatic investigations have identified numerous splice variants, but whether these transcripts are translated to functional proteins and the physiological significance of...

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Bibliographic Details
Main Authors: Heinzen, E, Yoon, W, Weale, M, Sen, A, Wood, N, Burke, JR, Welsh-Bohmer, K, Hulette, C, Sisodiya, S, Goldstein, D
Format: Journal article
Language:English
Published: 2007