Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease.
BACKGROUND: Alternative gene transcript splicing permits a single gene to produce multiple proteins with varied functions. Bioinformatic investigations have identified numerous splice variants, but whether these transcripts are translated to functional proteins and the physiological significance of...
Main Authors: | Heinzen, E, Yoon, W, Weale, M, Sen, A, Wood, N, Burke, JR, Welsh-Bohmer, K, Hulette, C, Sisodiya, S, Goldstein, D |
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Format: | Journal article |
Language: | English |
Published: |
2007
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