Structural/mechanistic insights into the efficacy of nonclassical β-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates
Clavulanic acid and avibactam are clinically deployed serine β-lactamase inhibitors, important as a defence against antibacterial resistance. Bicyclic boronates are recently discovered inhibitors of serine and some metallo β-lactamases. Here, we show that avibactam and a bicyclic boronate inhibit L2...
Үндсэн зохиолчид: | Calvopiña, K, Hinchliffe, P, Brem, J, Heesom, K, Johnson, S, Cain, R, Lohans, C, Fishwick, C, Schofield, C, Spencer, J, Avison, M |
---|---|
Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Wiley
2017
|
Ижил төстэй зүйлс
Ижил төстэй зүйлс
-
Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates.
-н: Calvopiña, K, зэрэг
Хэвлэсэн: (2016) -
Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates
-н: Cahill, S, зэрэг
Хэвлэсэн: (2019) -
Mechanistic insights into β-lactamase-catalysed carbapenem degradation through product characterisation
-н: Lohans, C, зэрэг
Хэвлэсэн: (2019) -
Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates
-н: Brem, J, зэрэг
Хэвлэсэн: (2016) -
Cyclic Boronates Inhibit All Classes of β-Lactamase.
-н: Cahill, S, зэрэг
Хэвлэсэн: (2017)