Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.

FIH (Factor inhibiting hypoxia-inducible factor), an asparaginyl beta-hydroxylase belonging to the super-family of 2-oxoglutarate and Fe(II)-dependent dioxygenases, catalyses hydroxylation of Asn-803 of hypoxia-inducible factor, a transcription factor that regulates the mammalian hypoxic response. O...

Полное описание

Библиографические подробности
Главные авторы: Lancaster, D, McDonough, M, Schofield, C
Формат: Journal article
Язык:English
Опубликовано: 2004