Distinctive patterns of transcription and RNA processing for human lincRNAs

Numerous long intervening noncoding RNAs (lincRNAs) are generated from the mammalian genome by RNA polymerase II (Pol II) transcription. Although multiple functions have been ascribed to lincRNAs, their synthesis and turnover remain poorly characterized. Here, we define systematic differences in tra...

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Detalhes bibliográficos
Principais autores: Schlackow, M, Nojima, T, Gomes, T, Dhir, A, Carmo-Fonseca, M, Proudfoot, N
Formato: Journal article
Idioma:English
Publicado em: Elsevier 2016