A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype.

OBJECTIVES: The aim of this study was to assess if genetic variation in the PACE4 (paired amino acid converting enzyme 4) gene Pcsk6 influences the risk for symptomatic knee osteoarthritis (OA). METHODS: Ten PCSK6 single nucleotide polymorphisms were tested for association in a discovery cohort of...

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Bibliographic Details
Main Authors:	Malfait, A, Seymour, AB, Gao, F, Tortorella, MD, Graverand-Gastineau, L, Wood, L, Doherty, M, Doherty, S, Zhang, W, Arden, N, Vaughn, F, Leaverton, P, Spector, T, Hart, D, Maciewicz, R, Muir, K, Das, R, Sorge, R, Sotocinal, S, Schorscher-Petcu, A, Valdes, A, Mogil, J
Format:	Journal article
Language:	English
Published:	2012

A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype.

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