Gold-catalyzed cyclization of yndiamides with isoxazoles via α-imino gold Fischer carbenes

Gold catalysis is an important method for alkyne functionalization. Here we report the gold-catalyzed formal [3+2] aminative cyclization of yndiamides and isoxazoles in a direct synthesis of polysubstituted diaminopyrroles, which are important motifs in drug discovery. Key to this process is the for...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Tong, Z, Smith, PJ, Pickford, HD, Christensen, KE, Anderson, EA
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Wiley 2023