CD2 sets quantitative thresholds in T cell activation.

It has been proposed that CD2, which is highly expressed on T cells, serves to enhance T cell-antigen presenting cell (APC) adhesion and costimulate T cell activation. Here we analyzed the role of CD2 using CD2-deficient mice crossed with transgenic mice expressing a T cell receptor specific for lym...

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Bibliographic Details
Main Authors: Bachmann, M, Barner, M, Kopf, M
Format: Journal article
Language:English
Published: 1999