Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.

Geahča maid

• Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.
  Dahkki: Hamed, R, et al.
  Almmustuhtton: (2010)
• Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.
  Dahkki: Sleeman, M, et al.
  Almmustuhtton: (2005)
• Thioester hydrolysis and C-C bond formation by carboxymethylproline synthase from the crotonase superfamily.
  Dahkki: Batchelar, E, et al.
  Almmustuhtton: (2008)
• Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases.
  Dahkki: Hamed, R, et al.
  Almmustuhtton: (2011)
• Application of affinity adsorption in thienamycin fermentation /
  Dahkki: 307099 Wang, Henry Y., et al.