Varicella-Zoster virus ORF9 Is an antagonist of the DNA sensor cGAS
Varicella-Zoster virus (VZV) causes chickenpox and shingles. Although infection is associated with severe morbidity in some individuals, the molecular mechanisms that determine innate immune responses remain poorly defined. We found that the cGAS/STING DNA sensing pathway was critically required for...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Cold Spring Harbor Laboratory
2020
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