A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host–pathogen interactions

Background: Sporozoite invasion of hepatocytes is an essential step in the Plasmodium life-cycle and has similarities, at the cellular level, to merozoite invasion of erythrocytes. In the case of the Plasmodium blood-stage, efforts to identify host–pathogen protein–protein interactions have yielded...

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Main Authors: Segireddy, RR, Belda, H, Yang, ASP, Dundas, K, Knoeckel, J, Galaway, F, Wood, L, Quinkert, D, Knuepfer, E, Treeck, M, Wright, GJ, Douglas, AD
Format: Journal article
Language:English
Published: BioMed Central 2024