Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.

The endocrine part of the pancreas plays a central role in blood-glucose regulation. It is well established that an elevation of glucose concentration reduces secretion of the hyperglycaemia-associated hormone glucagon from pancreatic alpha 2 cells. The mechanisms involved, however, remain unknown....

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Bibliographic Details
Main Authors: Rorsman, P, Berggren, P, Bokvist, K, Ericson, H, Möhler, H, Ostenson, C, Smith, P
Format: Journal article
Language:English
Published: 1989