FRMD8 is a novel regulator of iRhom-dependent ADAM17 activity
<p>A disintegrin and metalloprotease (ADAM) 17 cleaves and releases membrane-tethered pro-forms of several signalling molecules from the plasma membrane, including the inflammatory cytokine tumour necrosis factor alpha (TNFα) and ligands of the epidermal growth factor receptor (EGFR). Due to t...
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| Format: | Thesis |
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2017
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