A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan.

BACKGROUND: Pregnancy is associated with an increased risk of developing a malaria infection and a higher risk of developing severe malaria. The pharmacokinetic properties of many anti-malarials are also altered during pregnancy, often resulting in a decreased drug exposure. Piperaquine is a promisi...

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Bibliographic Details
Main Authors: Hoglund, R, Adam, I, Hanpithakpong, W, Ashton, M, Lindegardh, N, Day, N, White, N, Nosten, F, Tarning, J
Format: Journal article
Language:English
Published: 2012