Exon 3 beta-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome.
BACKGROUND AND AIMS: Activating beta-catenin mutations in exon 3 have been implicated in colorectal tumorigenesis. Although reports to the contrary exist, it has been suggested that beta-catenin mutations occur more often in microsatellite unstable (MSI+) colorectal carcinomas, including hereditary...
Հիմնական հեղինակներ: | , , , , , , , , , , , , |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2005
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