Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches.

We have used bandshift analysis to measure the interaction between the Escherichia coli mismatch-binding protein MutS and synthetic DNA fragments containing all possible DNA mismatches as well as an unpaired T (DeltaT). The order of affinity is found to be DeltaT>GT>GG>AA approx...

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Autors principals: Brown, J, Brown, T, Fox, K
Format: Journal article
Idioma:English
Publicat: 2001